卵巢癌胸腔转移50例临床分析

 自1958年3月至1987年2月,我院收治的616例卯巢恶性肿瘤病人中,有8%(50/616)发现有胸腔转移。其中上皮癌、生殖细胞癌,卵巢颗粒泡膜细胞瘤和其他类型癌胸腔转移的发生率各为8.4%(30/356),8.6%(10/116),7.1%(4/56),6.8%(6/88)。50例中治疗开始发现有胸腔转移者26例,治疗中或治疗后出现转移者24例。胸腔转移的类型最常见的是胸腔积液34例(68%),依次是肺实质转移16例(32%),重复并纵膈转移4例 (0.8%),心包转移3例(0.8%)本组平均追髓14.9个月,60%(30/50)和80%(40/50)病人死于一年和二年内。除4例随访中外,46例死亡病人的中位数生存是8.5个月。有9例病人经过积极处理原发肿瘤,胸腔内转移以及术后多疗程联合化疗,生存22—96个月,中位数生存35.5个月,1例无癌生存8年以上,说明卵巢癌胸腔转移病人经积极治疗可延长寿命,极少数病人可治愈。

INTRA-THORACIC METASTASIS FROM OVARIAN CARCINOMA——REPORT ON 50 PATIENTS

Eight percent (50/616) of ovarian carcinoma patients, fiom March 1958 to February 1987 into our hospital, developed Jaffa-thoracic metastasis. The respective metastatic rates of epithelial carcinoma was 8.4% (30/356), germ cell carcinoma 8.6% (10/116), ovarian granulosa cell tumor 7.1% (4/56), add the others 6.8% (6/88). The jaffa-thoracic metastasis was discovered at the time of admission in 26 of these 50 patients and during or after treatment in 24. The manifestation most commonly observed was pleurisy with effusion (34/50cases), followed by lung-parenchymal metastases was 16 eases (32%), associated with metastases of mediastium (3cases) and paraeardic metastases (3 cases).Patients in the present series were followed for a mean duration of 14.9 months. Except the four surviving patients who are still being followed, the rest 46 dead patients gave a median survival of 8.5 months.