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南昌市甲型H1N1流感病例死亡因素分析
引用本文:熊志伟,胡茂红,李辉,吴景文,甘启芦,涂正波.南昌市甲型H1N1流感病例死亡因素分析[J].中国公共卫生,2011,27(10).
作者姓名:熊志伟  胡茂红  李辉  吴景文  甘启芦  涂正波
作者单位:南昌市疾病预防控制中心,江西,330006
摘    要:目的 探讨重症甲型H1N1流感病例死亡因素.方法应用病例对照研究方法,以江西省南昌市2009-2010年甲型H1N1流感死亡病例9例为病例组,重症病例治愈者66例为对照组,应用SPSS 13.0软件进行统计分析.结果2009 -2010年南昌市甲型H1N1流感重症病例发生率8.33%,病死率为1%;慢性肝脏疾病、孕妇、有创吸氧在死亡组比例明显高于重症组,差异有统计学意义(分别0R=25.6,95%CI =1.97~333.55;0R=12.67,95%CI =0.86~186.91;0R=10,95%CI =1.07~93.44);死亡组发生2种、≥3种并发症比例高于重症组,差异有统计学意义(分别0R=9.83,95%CI =1.17~82.94;0R=118,95%CI =8.72~1597).结论慢性肝脏疾病、心血管疾病、孕妇等基础性疾病、有创吸氧、出现基础性疾病以外并发症可能是重症甲型H1 N1流感病例死亡的危险因素,尽早发现以上病例,密切监控,调整治疗方案,降低病死率.

关 键 词:甲型H1N1流感  危险因素  病例对照研究

Risk factors associated with fatality among severe cases of pandemic influenza H1N1 in Nanchang city
XIONG Zhi-wei,HU Mao-hong,LI Hui,et al..Risk factors associated with fatality among severe cases of pandemic influenza H1N1 in Nanchang city[J].Chinese Journal of Public Health,2011,27(10).
Authors:XIONG Zhi-wei  HU Mao-hong  LI Hui  
Institution:XIONG Zhi-wei,HU Mao-hong,LI Hui,et al.Nanchang Municipal Center for Disease Control and Prevention,Jiangxi Province(Nanchang 330038,China)
Abstract:Objective To explore the risk factors associated with fatality among severe cases of pandemic influenza H1N1 in Nanchang city.Methods A case-control study was conducted with 9 cases of death and 66 severe cases of influenza H1N1 as controls.Results The ratio of the severe cases was 8.33% among all influenza A H1N1 patients.The mortality was 1%.The fatality of the cases with chronic liver disease,pregnancy,and invasive oxygen treatment was higher than that of severe cases with the odds ratio(OR)(95% confiden...
Keywords:influenza A H1N1  risk factor  case-control study  
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