正常人黄斑部视网膜神经上皮层厚度的分区测量

目的测量正常人黄斑部各分区的视网膜神经上皮层厚度(neurosensory retinal thickness,NRT)。方法应用光学相干断层成像术(optical coherence tomography,OCT3000)对60例(120眼)正常人的黄斑部进行扫描,扫描模式为快速黄斑厚度地形图(fast macular thickness map),分析模式为视网膜厚度/体积分析(retinal thickness/volume analysis),应用OCT3000自带软件分别测出9个分区和黄斑中心小凹的NRT及总黄斑体积。用SPSS11.0统计软件包分析不同年龄、眼别、性别组间上述指标有无统计学差异。结果不同年龄组间除黄斑中心小凹、上、下方外环区、总黄斑体积外(P<0.05),其余部位差异均无显著性;不同眼别间除鼻侧内环区、上、下方外环区、颞侧外环区外(P<0.05),其余部位差异均无显著性;不同性别间中央区、内环区各象限、鼻侧外环区、颞侧外环区、总黄斑体积差异有显著性(P<0.05)。结论OCT3000可用于测量黄斑部各分区的NRT,其厚度值存在年龄、眼别及性别差异。

Measurement of neurosensory retinal thickness in different macular sections of normal subjects

Objective To measure neurosensory retinal thickness in different macular sections of normal subjects.Methods Sixty normal subjects (120 eyes) underwent optical coherence tomography (OCT 3000) to obtain the neurosensory retinal thickness (NRT) of nine sections and the foveola, and the total macular volume. The scan model was a fast macular thickness map, and the analysis model was the retinal thickness/volume analysis. The effects of age, laterality and gender on macular thickness were analyzed with the SPSS11.0 program.Results There were no statistically significant differences between age groups except for the foveola, superior outer ring, inferior outer ring and total macular volume (P<0.05); there were no statistically significant differences between the two eyes except for the nasal inner ring, superior outer ring and inferior outer ring (P<0.05). There were statistically significant differences between genders in the central sector, in every quadrant of the inner ring, the nasal outer ring, the temporal outer ring and total macular volume (P<0.05).Conclusion OCT 3000 could be used to measure the thickness of the neurosensory retina. Differences exist between age groups, eyes and genders in some macular sections of normal subjects.