Recent advances in salmonellosis treatment based on in vitro susceptibilities |
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| Authors: | A G Paradelis T Edipides W Zurukzoglou |
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| Institution: | Department of Experimental Pharmacology, Medical Faculty, Aristotelian University of Thessaloniki, Greece. |
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| Abstract: | Chloramphenicol-resistant strains of Salmonella typhi (MIC 60 micrograms/ml), chloramphenicol and ampicillin-resistant strains of Salmonella typhimurium as well as multiresistant strains of various salmonella serotypes were found to be very sensitive to cephradine (MIC 0.078-0.625 micrograms/ml). Ten patients with Salmonella typhi bacteremia were successfully treated with cephradine; all the patients' strains were chloramphenicol-resistant. Cephradine appears to warrant further clinical trial for the treatment of salmonellosis. |
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