| 秋水仙碱对四氯化碳所致大白鼠慢性肝损害治疗作用的实验形态学观察 |
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| 引用本文： | 陈艳贤,张艳,蔡秋云,周洁萍,彭汉林,熊希凯,李绍白,唐望先,过晋源.秋水仙碱对四氯化碳所致大白鼠慢性肝损害治疗作用的实验形态学观察[J].华中科技大学学报(医学版),1984(5). |
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| 作者姓名： | 陈艳贤 张艳 蔡秋云 周洁萍 彭汉林 熊希凯 李绍白 唐望先 过晋源 |
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| 作者单位： | 武汉医学院基础医学部人体解剖教研室
(陈艳贤，张艳，蔡秋云，周洁萍，彭汉林，熊希凯)，武汉医学院第二附属医院肝胆研究室
(李绍白，唐望先)，武汉医学院第二附属医院肝胆研究室(过晋源) |
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| 摘 要： | 本文报告秋水仙碱治疗四氯化碳所致大白鼠慢性肝损害的胶原纤维和肝细胞酶活性、糖原和核糖核酸量的变化。所试动物以组织化学和组织学方法进行观察。结果提示秋水仙碱有抑制慢性肝损害胶原纤维形成的作用,但对肝细胞功能的恢复作用不明显。
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| 关 键 词： | 秋水仙碱 四氯化碳 慢性肝损害 治疗作用 |
The Effect of Treatment of Colchicine on Chronic Liver Damage Induced by CcI_4 in Rats: An Observation of Morophology |
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| Chen Yanxian,et al..The Effect of Treatment of Colchicine on Chronic Liver Damage Induced by CcI_4 in Rats: An Observation of Morophology[J].Journal of Huazhong University of Science and Technology(Health Sciences),1984(5). |
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| Authors: | Chen Yanxian |
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| Institution: | Chen Yanxian,et al.Department of Anatomy,Faculty of Basic Sciences,Wuhan Medical College,Wuhan |
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| Abstract: | The morophological change of chronic liver damage induced by Cclt in rats treated with colchicine was demonstrated with histochemical and histological methods. Collage-nous fiber of liver, activities of ATPase,G-6-Pase,SDH,LDH,ACP,ALP and contents of glycogen and RNA of liver cells were observed. These experimental results suggested that colchicine may inhibit the formation of collagenous fiber of liver of chronic damage, but the effect of colchicine on the recovering function of liver was not conspicuous. |
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| Keywords: | colchicine carbon tetrachloride chronic damage of liver effect of treatment |
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