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Boron neutron capture therapy combined with fractionated photon irradiation for glioblastoma: A recursive partitioning analysis of BNCT patients |
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| Authors: | K. Nakai T. Yamamoto H. Aiyama T. Takada F. Yoshida T. Kageji H. Kumada T. Isobe K. Endo M. Matsuda T. Tsurubuchi Y. Shibata S. Takano M. Mizumoto K. Tsuboi A. Matsumura |
| Affiliation: | aDepartment of Neurosurgery, Graduate School of Comprehensive Human Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan;bDepartment of Radiation Oncology, Graduate School of Comprehensive Human Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Japan;cDepartment of Neurosurgery, Tokushima University, 2-50-1 Kuramoto, Tokushima, Japan |
| Abstract: | Eight patients to received Boron Neuron Capture Therapy (BNCT) were selected from 33 newly diagnosed glioblastoma patients (NCT(+) group). Serial 42 glioblastoma patients (NCT(−) group) were treated without BNCT. The median OS of the NCT(+) group and NCT (−) group were 24.4 months and 14.9 months. In the high risk patients (RPA class V), the median OS of the NCT(+) group tended to be better than that of NCT(−) group. 50% of BNCT patients were RPA class V. |
| Keywords: | BNCT Glioblastoma Clinical study Recursive partitioning analysis |
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