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Human plasma-derived media supplement supports antibody production by hybridoma cells |
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| Authors: | Young Janet M. Zhang Da-Wei Tharakan John Jenkins Larry Collins Roger Drohan William N. |
| Affiliation: | (1) Jerome H. Holland Laboratory, American Red Cross, 15601 Crabbs Branch Way, 20855 Rockville, Maryland;(2) Present address: Department of Chemical Engineering, Howard University, 2300 6th Street, N.W., 20059 Washington, D.C. |
| Abstract: | Summary A new, virus-inactivated, media supplement from human plasma (GEMS) has been developed which maintains hybridoma cells at a low growth rate. The rate of antibody production per cell by hybridoma cells growing in the presence of GEMS is at least equivalent to the rate of antibody production by the same cell lines growing in fetal bovine serum. |
| Keywords: | human plasma-derived media supplement hybridoma antibody production |
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