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中药单体化合物免疫抑制活性的研究进展
引用本文:孙世芹,王有志,周亚滨.中药单体化合物免疫抑制活性的研究进展[J].中国中药杂志,2010,35(3):393-396.
作者姓名:孙世芹  王有志  周亚滨
作者单位:1. 哈尔滨医科大学药学系,黑龙江,大庆,163319;黑龙江中医药大学附属第一医院,黑龙江,哈尔滨,154040
2. 哈尔滨医科大学药学系,黑龙江,大庆,163319
3. 黑龙江中医药大学附属第一医院,黑龙江,哈尔滨,154040
基金项目:国家科技重大专项课题(2009ZX09103-425);黑龙江省博士后基金项目(LBH-Z06245)
摘    要:临床或实验研究表明,中药雷公藤、苏木、青风藤、天花粉及青蒿均具有良好的免疫抑制活性,对其免疫抑制活性成分的深入研究已经成为近年研究的主要方向.作者就近几年来从中药中获取的雷公藤红素、雷公藤内酯醇、巴西苏木红素、原苏木素A、青藤碱、天花粉蛋白及青蒿素等免疫抑制活性单体化合物的相关研究进展做简要综述.

关 键 词:免疫抑制  雷公藤  苏木  青风藤  天花粉  青蒿
收稿时间:2009/10/12 0:00:00

Research progress on immunosuppressive activity of monomersextracted from Chinese medicine
SUN Shiqin,WANG Youzhi and ZHOU Yabin.Research progress on immunosuppressive activity of monomersextracted from Chinese medicine[J].China Journal of Chinese Materia Medica,2010,35(3):393-396.
Authors:SUN Shiqin  WANG Youzhi and ZHOU Yabin
Institution:Harbin Medical University Daqing Campus, Department of Pharmacy, Daqing 163319, China;First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin 150036, China;Harbin Medical University Daqing Campus, Department of Pharmacy, Daqing 163319, China;First Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin 150036, China
Abstract:The clinical or experimental study proves that Chinese medicine such as Tripteryglum wilfordii , Lignum Sappan, Caulis Sinomenii, Radix Trichosanthis and Herba Artemisiae Annuae have good immunosuppressive activity. Further researches on the immunosuppressive active components from Chinese medicine have been the main direction in recent years. The recent researches on immunosuppressive effect and possible mechanisms for the monomers such as triperine, triptolide, bazilein, potosappanin A, sinomenine, trichosanthin and artemisinin extracted from those Chinese medicine are introduced in this review.
Keywords:immunosuppression  Tripteryglum wilfordii  Lignum Sappan  Caulis Sinomenii  Radix Trichosanthis  Herba Artemisiae Annuae
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