慢性肾小球疾病高血压及其对肾功能影响

目的了解慢性肾小球疾病时高血压发病情况及其对肾功能的影响.方法520例住院病例,按WHO及中华医学会制订的形态学分类标准分组观察.结果 高血压总发病率为32.7%,膜增生性肾炎、新月体肾炎及硬化性肾炎常发生高血压,而lgA肾病及微小病变肾病较少发生高血压.在疾病早期,肾功能正常或轻微异常时常已发生高血压,经降压治疗后肾功能可改善.结论 不同病理类型慢性肾小球疾病高血压发病率不同,降压治疗可改善肾功能并延缓肾功能恶化速率.

Arterial Hypertension and its influence on Renal Function in Chronic Glomerulonephritis

Aim To determine the frequeney of arterial hypertension in chronic glomerulonephri-tis. Methods Five hundred and twenty patients of chronic glomerulonephritis classifiedmorphologically according to the criteria of the WHO's and Chinese Medical Associationwere analyzed retrospectively. Results The overall prevalence of arterial hypertension was32. 7%. Hypertension was most frequent in membranoproliferative, extracapillary, and scle-rotic glomerulonephritis (P < 0. 05), but infrequent in IgA nephropathy and minimal lesion(P< 0. 01). Hypertension often developed during the early stage of the disease when renalfunction was normal or minimal abnormal. Renal function was often improved after antihy-pertension therapy. Conclusion The frequency of the hypertension in different subgroupwas different, and antihypertension therapy might improve renal function and slow down therate of progressive renal failure.