原发性开角型青光眼HRT视盘结构参数与视野缺损相关性研究

目的探讨出现视野缺损与未出现视野缺损的原发性开角型青光眼视盘结构参数的异同及视盘参数与视野平均缺损（MD）的相关性。方法应用海德堡视网膜断层扫描仪（HRT-Ⅱ）和Octopus101视野G2程序对29例（50只眼）原发性开角型青光眼患者进行检查，对出现视野缺损与未出现视野缺损的原发性开角型青光眼视盘结构参数进行比较，检测结果进行t检验；对出现视野缺损的原发性开角型青光眼组的视盘各参数与视野平均缺损进行简单相关分析。结果视野出现缺损组与未出现缺损组的原发性开角型青光眼患者的视盘参数除视盘面积和轮廓线高度变化值外，其余各视盘参数间差异均有显著性（P〈0．01）；对出现视野缺损的原发性开角型青光眼患者HRT视盘各参数与MD进行相关分析显示，盘沿面积与MD间相关性最强（r=0．65，P=0．001）。结论HRT视盘参数能够较准确反映与视野损害相一致的青光眼性视盘改变，盘沿面积在HRT众多参数中最能反映青光眼的视野平均缺损程度。

Compare the correlation between stereometric parameters of optic disc and visual defects in primary open-angle glaucoma

Objectives To investigate the differences and similarities of stereometric parameters of optic disc be- tween the primary open-angle glaucoma patients (POAG) with the glaucomatous visual field (VF) defect and without VF de- feet,and the relativity between the stereometric parameters of optic disc and mean defect (MD) in visual field.Methods 50 eyes of 29 cases of POAG were examined with HRT and G2 program of Octopus 101 Perimeter.The optic disc parame- ters between the POAG patients with the glaucomatous visual field (VF) defect and without VF defect were compared,The Results Were analyzed for T-test;The optic disc parameters of the POAG patients with the glaucomatous VF defect were analyzed for the correlation with mean defect in visual field.Results There were remarkable differences in optic disc param- eters except for DA,HVC between the POAG patients with the glaucomatous visual field (VF) defect and without VF defect (P<0.01).The stereometric parameters of optic disc of the POAG patients with the glaucomatous VF defect were ana- lyzed for simple correlation with MD of visual field,RA was most obviously significant relationship with MD(r=0.65,P =0.001).Conclusion The optic disc parameters were examined by HRT can well reflect the optic disc damage that were consistent with the glaucomatous VF defect.In all of the optic disc parameters of HRT,RA can reflect the glaucomatous visual field loss best.