| Experimental study of the effect of platelet-rich plasma on osteogenesis in rabbit |
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| 引用本文： | 张长青 袁霆 曾炳芳. Experimental study of the effect of platelet-rich plasma on osteogenesis in rabbit[J]. 中华医学杂志(英文版), 2004, 117(12): 1853-1855 |
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| 作者姓名： | 张长青 袁霆 曾炳芳 |
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| 作者单位： | DepartmentofOrthopaedics,ShanghaiSixthPeople＇sHospital,ShanghaiJiaotongUniversity,Shanghai200233,China |
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| 基金项目： | NationalnaturalScienceFoundationof China(No.30471747) |
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| 摘 要： | Platelet-rich plasma (PRP) is produced from a patient‘s own blood by centrifugation, and PRP contains several kinds of growth factors in high concentration such as platelet derived growth factor (PDGF), transforming growth factor-β( TGF-β ), vascular endothelial growth factor ( VEGF ), insulin-like growthepidermal growth factor ( EGF ), and so on. These growth factors have proved to offer an improved quality and speed of healing for both hard and soft tissue. In this study, PRP compounded with porous bioceramic was used to repair a bone defect in rabbit radius. The radiographic and histological qualitative and quantitative observations were performed to evaluate osteogenesis.
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| 关 键 词： | 实验研究 TGF-β 血小板充足血浆 骨生生成 VEGF |
Experimental study of the effect of platelet-rich plasma on osteogenesis in rabbit |
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| Abstract: | |
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| Keywords: | platelet-rich plasma bone defect osteogenesis bioceramic |
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