A study of urinary and intracellular sodium and potassium, renin, aldosterone, and hypertension in blacks and indians in natal

The prevalence of hypertension in the urban black population in Sub-Saharan Africa is high and varies from 20% to 25%. In contrast, the prevalence of hypertension in the rural black is relatively low. In Natal the prevalence of hypertension in a large metropolitan city, Durban, is 25% in the adult Zulu, 17.2% in whites, and 14.2% in Indians. The prevalence of hypertension in the rural Zulu of Natal is 10%. Work on the pathogenesis of hypertension in the Zulu and Indian ethnic groups related to renin, aldosterone, dietary sodium and potassium, and intracellular sodium and potassium was virtually nonexistent. This review paper summarizes the salient features that were found. This paper is a summary of the work undertaken by Dr. S. Hoosen in partial fulfillment of the requirements for the Degree of Doctor of Medicine in the University of Natal, 1988.