| 血清降钙素原和C-反应蛋白在慢性支气管炎急性发作期患者中的临床评价 |
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| 引用本文： | 胡小佳,周芳,裘宇容,李强. 血清降钙素原和C-反应蛋白在慢性支气管炎急性发作期患者中的临床评价[J]. 南方医科大学学报, 2010, 30(7) |
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| 作者姓名： | 胡小佳 周芳 裘宇容 李强 |
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| 作者单位： | 南方医科大学南方医院检验科,广东,广州,510515;南方医科大学南方医院检验科,广东,广州,510515;南方医科大学南方医院检验科,广东,广州,510515;南方医科大学南方医院检验科,广东,广州,510515 |
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| 摘 要： | 目的 评价血清降钙素原(PCT)和C-反应蛋白(CRP)对慢性支气管炎(慢支)急性发作期的诊断价值.方法 56例慢支急性发作期患者作为观察组,58例健康查体者为对照组,比较分析两组血清PCT和CRP结果.结果 (1)观察组血清PCT水平显著高于对照组,两组相比较差异有统计学意义(P<0.05);观察组的PCT检测阳性率为94.6%,高于对照组(15.5%),两组比较均有显著性差异(P<0.05).(2)观察组血清CRP水平显著高于对照组,两组相比较有显著性差异(P<0.05);观察组的CRP检测阳性率为30.4%,高于对照组(22.4%),但两组比较差异无统计学意义(P>0.05).(3)PCT检测对慢支急性发作期诊断的灵敏度、特异度、阳性预测值、阴性预测值和诊断符合率均高于CRP.结论 PCT对慢支急性发作期的诊断较CRP敏感,血清PCT水平可以作为慢支急性发作期的特异性监测指标.
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| 关 键 词： | 降钙素原 C-反应蛋白 慢性支气管炎 急性发作 |
Diagnostic value of serum procalcitonin and C-reaction protein in acute exacerbation of chronic bronchitis |
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| HU Xiao-Jia,ZHOU Fang,QIU Yu-Rong,LI Qiang. Diagnostic value of serum procalcitonin and C-reaction protein in acute exacerbation of chronic bronchitis[J]. Nan Fang Yi Ke Da Xue Xue Bao, 2010, 30(7) |
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| Authors: | HU Xiao-Jia ZHOU Fang QIU Yu-Rong LI Qiang |
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| Affiliation: | HU Xiao-Jia,ZHOU Fang,QIU Yu-Rong,LI Qiang Department of Laboratory Medicine,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China |
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| Abstract: | Objective To evaluate the diagnostic value of serum procalcitonin (PCT) and C-reactive protein (CRP) in patients with acute exacerbation of chronic bronchitis. Methods The PCT and CRP levels were detected in 56 patients with acute exacerbation of chronic bronchitis and 58 healthy control subjects. Results The serum PCT level and positivity rate were significantly higher in the case group than in the control group (P<0.05); the serum CRP level was also significantly higher in the case group (P<0.05), but the... |
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| Keywords: | serum procalcitonin c-reaction protein chronic bronchitis acute exacerbation |
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