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三七止血片中三七含量测定
引用本文:沙延淳,叶小辉,杨祝仁,姚建华.三七止血片中三七含量测定[J].辽宁中医学院学报,2013(8):48-49.
作者姓名:沙延淳  叶小辉  杨祝仁  姚建华
作者单位:[1]辽宁省药物研究院,辽宁沈阳110015 [2]辽宁中医药大学,辽宁大连116600
摘    要:目的:对三七止血片中三七的主要成分进行测定,提高质控标准。方法:采用液相梯度法以人参皂苷Rg1、人参皂苷Rb1和三七皂苷R1的含量为指标。结果:测定三七止血片中人参皂苷Rg12.42 mg/片,人参皂苷Rb11.37 mg/片,三七皂苷R10.15 mg/片,含皂苷总量为3.94 mg/片。结论:液相梯度法方法可控,可以达到提高药品质量控制的目的。

关 键 词:三七止血片  三七  含量

Determination of Contents of Ginsenoside Rgl, Ginsenoside Rbl and Notoginsenoside R1 in Notoginseng Hemostasis Tablet
SHA Yanchun,YE XiaohuiI,YANG ZhurenI,YAO Jianhua.Determination of Contents of Ginsenoside Rgl, Ginsenoside Rbl and Notoginsenoside R1 in Notoginseng Hemostasis Tablet[J].Journal of Liaoning College of Traditional Chinese Medicine,2013(8):48-49.
Authors:SHA Yanchun  YE XiaohuiI  YANG ZhurenI  YAO Jianhua
Institution:2 ( 1.Liaoning Institute of Pharmaceutical Industry, Shenyang 110015, Liaoning, China ; 2.Liaoning University of Traditional Chinese Medicine, Dalian 116600, Liaoning, China )
Abstract:Objective: Determination of the contents of main components in notoginseng hemostasis tablet was made to improve the standard of quality. Methods : The contents of ginsenoside Rgl, ginsenoside Rbl and the notoginsenoside R1 were set up as the indexes by HPLC gradient profile. Results : The contents of ginsenoside Rgl, ginsenoside Rbland the notoginsenoside R1 were 2.42 mg per tablet, 1.37 mg per tablet and 0.15 mgper tablet respectively. 3.94 mg per tablet was the total saponin content. Conclusion:The exneriment of HPLC zradient orofile could reach the ~oal by improving quality control of the drug.
Keywords:notoginseng hemostasis tablet  notoginseng  content
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