2型糖尿病瘀热证与脂代谢紊乱及糖尿病病程相关性研究

目的：探讨2型糖尿病瘀热证与脂代谢紊乱及糖尿病病程之间的关系,寻找糖尿病瘀热证临床客观指标,为糖尿病瘀热证诊疗提供客观依据。方法：收集符合2型糖尿病瘀热证诊断标准的患者共计143例,对其瘀热证证候进行积分,分为轻（A）、中（B）、重（C）3组。检测各组患者血脂（TC、TG、HDL-C、LDL-C）,记录各组患者病程。结果：3组间比较：TC、LDL-C差异具有显著性,病程长短具有差异性。3组间TC、LDL-C及病程随瘀热程度呈升高趋势。2型糖尿病瘀热证患者瘀热证候积分与TC、LDL-C呈显著正相关（P〈0.01）,与TG及病程呈正相关（P〈0.05）。结论：2型糖尿病瘀热证患者瘀热程度与其病程及TC、TG、LDL-C呈正相关,随瘀热程度的加深,病程及TC、LDL-C呈上升趋势。

Study on Correlation among Stagnated Heat Syndrome of Type 2 Diabetes Liqid Metabolic and Disease Course

Objective ： To explore the relationship between stagnanted heat syndrome of type 2 diabetes and dyslipidemia and course, looking for the clinical objective index, and providing objective basis for diagnosis and treatment of it. Methods ： It was conducted 143 patients with the syndrome of stagnated heat of type 2 diabetes who were divided into mild （ A ）, moderate （ B ）, and serious （ C ） three groups.Detection of serum lipids in patients in each group （ TC, TG, HDL-C, LDL-C ） was carried out and the course of disease in patients in each group was recorded. Results ： The comparison among three groups ： TC and LDL-C had significant difference ; the length of the course had the difference.Among the three groups, TC, LDL-C and duration were increased with the degree of heat and blood stasis. A significant positive correlation existed between stagnanted heat syndrome of type 2 diabetes in patients with integral and TC, LDL-C （P〈0.01）, and positively relates to TG and disease duration （ P〈0.05 ） .Conclusion ： There is a positive correlation between stagnated heat syndrome in type 2 diabetes and levels of TC, TG, LDL-e as well as the disease course. With the increasing stagnated heat levels of TC, TG, LDL-c and disease courses have an increased trend.