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Authors:Hignett  M; Spence  JEH; Claman  P
Institution:University of Ottawa, Ottawa Civic Hospital 1053 Carling Avenue, Ottawa, Ontario, K1Y 4E9, Canada
Abstract:Thromboembolic events are serious but rare complications followingovarian stimulation for in-vitro fertilization (IVF). We reporta case of severe ovarian hyperstimulation syndrome (OHSS), presentingin a second IVF cycle with a late complication of right internaljugular vein thrombosis despite mini-dose heparin prophylaxis.Thrombosis and thromboembolism as late complications of OHSShave been reported by others but not after prophylactic heparinization.The patient was successfully treated with heparin and the twinpregnancy is ongoing. In pregnant patients with severe OHSSconsideration should be given to treatment with low dose heparinthroughout the first trimester to prevent the serious complicationsof thrombosis and thromboembolism.
Keywords:mini-dose/heparin/prophylaxis/ovarian/hyperstimulation/syndrome/thrombosis
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