Private specificity of H-2Ldx molecule detected serologically by a surface antigen redistribution method (capping)

The presence of H-2·1 positive-H-2·63 negative molecules, H-2L^dx, in the products of the ^dx region was originally detected in H-2^dx inbred strains GRS/A and LIS/A (Snoek et al. 1979).
This study confirms the existence of H-2L^dx molecules in 2 congeneic strains with a H-2^dx haplotype on C3H (C3H·LG strain) and B10 (B10·GR strain) background. Besides anti-H-2·1-like antibodies present in anti-D^dx allo-antiserum, monoclonal antibody d anti- k (H100-5/28, H-2·m3) was shown to react with H-2L^dx molecule. Furthermore, evidence is shown that H-2L^dx molecule has a unique specificity, which is detected serologically in a capping experiment.