| Establishment of VX2 breast carcinoma model in rabbit by injecting tumormass suspension |
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| 作者姓名： | 陈江浩 姚青 王岭 凌瑞 张聚良 王廷 王辉 杨华 |
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| 作者单位： | [1]DepartmentofVascularandEndocrineSurgery,XijingHospital,FourthMilitaryMedicalUniversity,Xi＇an710032,China [2]DepartmentofVascularandEndocrineSurgery,XijingHospital,FourthMilitaryMedicalUniversity,Xi＇an710032,China |
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| 摘 要： | To establish a stable model of VX2 breast carcinoma in rabbit and select the optimal way. Methods: Thirty female New Zealand rabbits were randomly divided into 3 groups with 10 in each. Tumor cell suspensions or tumor mass suspensions were injected into breast tissues of rabbits of group A and B, respectively. Tumor blocks were surgically implanted in rabbit breasts of group C. Tumor formation rate, tumor growth rate, and tumor-beating survival time was companY, and the histological feature of tumor was observed. Results: Models were established conveniently and successfully in rabbits received injection of tumor mass suspensions. Tumor proliferated rapidly with the biological feature of squamous cell carcinoma. Conelusion: VX2 breast carcinoma model in rabbit was established successfully. Intrmnammary injection of tumor mass suspension is the best method.
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| 关 键 词： | VX2癌 胸部癌模型 兔 动物模型 注射治疗 癌肿 肿瘤 |
Establishment of VX2 breast carcinoma model in rabbit by injecting tumor mass suspension |
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| CHEN Jiang-hao,YAO Qing,WANG Ling,LING Rui,ZHANG Ju-liang,WANG Ting,WANG Hui,YANG Hua.Establishment of VX2 breast carcinoma model in rabbit by injecting tumormass suspension[J].Journal of Medical Colleges of PLA(China),2004,19(3):161-163. |
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| Authors: | CHEN Jiang-hao YAO Qing WANG Ling LING Rui ZHANG Ju-liang WANG Ting WANG Hui YANG Hua |
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| Institution: | CHEN Jiang-hao,YAO Qing,WANG Ling,LING Rui,ZHANG Ju-liang,WANG Ting,WANG Hui,YANG Hua Department of Vascular and Endocrine Surgery,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China |
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| Abstract: | Objective: To establish a stable model of VX2 breast carcinoma in rabbit and select the optimal way. Methods: Thirty female New Zealand rabbits were randomly divided into 3 groups with 10 in each. Tumor cell suspensions or tumor mass suspensions were injected into breast tissues of rabbits of group A and B, respectively. Tumor blocks were surgically implanted in rabbit breasts of group C. Tumor formation rate, tumor growth rate, and tumor-bearing survival time was compared, and the histological feature of tumor was observed. Results: Models were established conveniently and successfully in rabbits received injection of tumor mass suspensions. Tumor proliferated rapidly with the biological feature of squamous cell carcinoma. Conclusion: VX2 breast carcinoma model in rabbit was established successfully. Intramammary injection of tumor mass suspension is the best method. |
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| Keywords: | breast carcinoma VX2 carcinoma animal model rabbit |
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