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| 4厂家产枸橼酸他莫昔芬片的溶出度考察 | |
| 引用本文： | 王瑞芹,杜青,薛健梅,张莹.4厂家产枸橼酸他莫昔芬片的溶出度考察[J].中国药房,2002,13(7):431-432. |
| 作者姓名： | 王瑞芹 杜青 薛健梅 张莹 |
| 作者单位： | 1. 河北医科大学附属第四医院药剂科,石家庄市050011 2. 河北医科大学药剂教研室,石家庄市050017 3. 河北医科大学药学院97级,石家庄市050017 |
| 摘 要： | 目的 :考察枸橼酸他莫昔芬片的溶出度。方法 :采用转篮法和浆法对国内4家制药厂生产的枸橼酸他莫昔芬片的溶出度进行了测定 ,并对溶出度参数Td 进行方差分析。结果 :转篮法和浆法测得的不同厂家产品的Td 值均有显著性差异 ,同一厂家产品的Td值转篮法小于浆法。结论 :不同厂家枸橼酸他莫昔芬片的溶出度存在显著性差异 |
| 关 键 词： | 枸橼酸他莫昔芬片 溶出度试验 转篮法 浆法 |
| 文章编号： | 1001-0408(2002)07-0431-02 |
| 修稿时间： | 2001年7月31日 |
Investigation on the Dissolubilities of Tamoxifen Citrate Tablets Produced by Four Different Factories |
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| WANG Ruiqin.Investigation on the Dissolubilities of Tamoxifen Citrate Tablets Produced by Four Different Factories[J].China Pharmacy,2002,13(7):431-432. | |
| Authors: | WANG Ruiqin |
| Abstract: | OBJECTIVE:To compare the dissolubilities of Tamoxifen citrate tablets from four domestic pharmaceutical factories METHODS:Rotating basket method and paddle method were used,and Td were calculated by Weibull distribution RESULTS:Statistical analysis showed that there were significant differences in Td among the products from different factories,and the dissolubility of the same product detected by rotating basket was slower than that by paddle method CONCLUSION:The dissolubilities of Tamoxifen citrate tablets have significant differences among four different domestic products |
| Keywords: | Tamoxifen citrate tablet dissolubility test rotating basket method paddle method |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |