慢性阻塞性肺疾病合并肺癌发病机制的研究进展

据统计,目前慢性阻塞性肺疾病(COPD)在全球40岁以上人群中发病率高达9%～10%.而世界卫生组织最新数据显示,肺癌发病率占全球新发癌症的11. 6%,病死率达18. 4%,是中国乃至全球发病率和病死率最高的癌症. COPD合并肺癌的年发病率为16. 7%,且仍在上升. COPD合并肺癌治疗难度大,需在两种疾病基础上...

Research pregress of pathogenesis of chronic obstructive pulmonary disease complicated with lung cancer

According to statistics,the global incidence of chronic obstruction pulmonary disease(COPD)in the population aged over 40 years old is as high as 9%-10%at present.According to the latest data by Word Health Organization,lung cancer accounts for 11.6%of all new cancer cases in the world,with a case fatality rate of 18.4%.The lung cancer has the highest incidence rate and case fatality rate in China and even in the world.The annual incidence of COPD with lung cancer is 16.7%and is still rising.COPD with lung cancer is difficult to treat because a treatment plan should be considered both diseases.With a high fatality rate,the comorbidity poses a great burden on medical resources.The pathogenesis of COPD with lung cancer is complex,and COPD itself is a risk factor for lung cancer.In this paper,we reviewed the recent progress in the pathogenesis of COPD with lung cancer.