经皮穿刺椎体成形术联合开放减压治疗跳跃性多发脊柱转移瘤的疗效

目的 探讨经皮穿刺椎体成形术（percutaneous vertebroplasty，PVP）联合开放减压治疗跳跃性多发脊柱转移瘤的临床疗效。方法 收集2013年1月至2019年12月本院收治的96例跳跃性多发脊柱转移瘤患者的临床资料，观察术中出血量，术前和术后VAS评分、KPS评分及ASIA神经损伤分级的变化以及手术并发症发生情况。结果 本研究中96例患者均顺利完成PVP联合开放减压治疗，术后1个月VAS评分较术前降低［（1.0±0.6） 分 vs （8.5±1.8） 分，P<0.001）］、术后3个月KPS评分高于术前［（75.0±18.2） 分 vs （45.0±10.5） 分，P<0.001）］。术后1个月87.5%的患者ASIA分级得到改善，其中D级和E级患者占比由术前的11.4%和0分别增多至40.6%和29.2%。结论 PVP联合开放减压治疗跳跃性多发脊柱转移瘤患者可以明显缓解疼痛，改善生活质量，有效解除脊髓压迫并不同程度地恢复受损神经功能。

An analysis of the clinical efficacy of percutaneous vertebroplasty combined with posterior decompression in the treatment of multiple jumping spinal metastasis

Objective To investigate the clinical efficacy of percutaneous vertebroplasty(PVP) combined with posterior decompression in the treatment of multiple jumping spinal metastasis tumor patients. Methods The clinical data of 96 patients with multiple jumping spinal metastasis tumor admitted to our hospital from January 2013 to December 2019 were collected, and intraoperative blood loss, the VAS score, KPS score and ASIA nerve injury grading before and after surgery were observed. Results A total of 96 patients were successfully completed PVP combined with posterior decompression therapy. The VAS score was decreased at 1 month after surgery ［(1.0±0.6) points vs (8.5±1.8) points, P<0.001)］, and the KPS score was increased at 3 months after surgery ［(75.0±18.2) points vs (45.0±10.5) points, P<0.001)］. One month after surgery, the ASIA grades of 87.5% patients were improved, and the proportion of patients with grade D and E were increased from 11.4% and 0% to 40.6% and 29.2%, respectively. Conclusion The treatment of percutaneous vertebroplasty combined with posterior decompression in multiple jumping spinal metastasis tumor patients can significantly relieve pain, improve quality of life, effectively relieve the spinal cord and restore damaged nerve function to various degree.