健康足月妊娠孕妇血栓弹力图参考范围的探讨

目的 探讨血栓弹力图(TEG)在健康足月妊娠孕妇凝血功能中的应用价值.方法 选取2016年3月-2018年3月本院收治健康足月妊娠孕妇80例为观察组,并选择该期间健康非妊娠女性80人为对照组.2组女性入院时行TEG、凝血检查.对比2组血浆凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋...

Study on reference range of thrombus elastography (TEG) in healthy full-term pregnant women

Objective To explore the value of thrombus elastography (TEG) in the coagulation function of healthy full-term pregnant women. Methods From March 2016 to March 2018, 80 healthy full-term pregnant women were selected as a trial group, and 80 healthy non-pregnant women were selected as a control group. TEG and coagulation examinations were performed on admission in both groups. The plasma prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen (FIB), and the R value, K value, MA value, CI value, and Lyn30 value of TEG were investigated and compared between the two groups. Results The time of PT (9.84±1.36) s, APTT (26.73±2.58) s, and TT (12.25±2.06) s in the trial group was shorter than that in the control group ; FIB (4.69±1.23) g/L in the trial group was higher than that in the control group ; R (4.48±1.37) min, K (1.32±0.31) min, and LY30 (0.29±0.88) %) in the trial group were lower than those in the control group ; MA (67.94±5.58) min, and CI (1.47) in the trial group were significantly higher than those in the control group . Conclusion The coagulation function of healthy full-term pregnant women is significantly different from that of the normal non-pregnant women. TEG under the normal conditions is not suitable for evaluating the coagulation function of women during pregnancy. Therefore, the reference range of TEG during pregnancy should be established, which has a great value for timely prediction, diagnosis, and treatment of abnormal bleeding.