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| 雷公藤与4种中药饮片配伍对雷公藤内酯醇的影响 | |
| 引用本文： | 王瑜,张喆,张志勇.雷公藤与4种中药饮片配伍对雷公藤内酯醇的影响[J].华西药学杂志,2007,22(4):431-432. |
| 作者姓名： | 王瑜 张喆 张志勇 |
| 作者单位： | 1. 四川大学华西医院,四川,成都,610041;四川大学华西药学院,四川,成都,610041 2. 四川大学华西药学院,四川,成都,610041 3. 四川大学华西医院,四川,成都,610041 |
| 摘 要： | 目的 研究赤芍、莱菔子、佛手、竹茹与雷公藤配伍后对雷公藤内酯醇的影响.方法 4种饮片分别与雷公藤配伍,加水提取,用HPLC测定雷公藤单提液及其配伍提取液中的雷公藤内酯醇.结果 佛手-雷公藤配伍提取液中雷公藤内酯醇约增加25%(P＜0.05).其余配伍提取液中雷公藤内酯醇无显著变化.结论 佛手和雷公藤配伍能明显增加提取液中雷公藤内酯醇,其余配伍对雷公藤内酯醇无显著影响. |
| 关 键 词： | 雷公藤 配伍 雷公藤内酯醇 雷公藤内酯醇 中药 饮片 醇的影响 drugs crude Chinese four compatible Tripterygium wilfordii triptolide 变化 结果 提取液 提液 测定 HPLC 水提取 方法 竹茹 |
| 文章编号： | 1006-0103（2007）04-0431-02 |
| 修稿时间： | 2006-12 |
Content change of triptolide in Tripterygium wilfordii compatible with four Chinese crude drugs |
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| WANG Yu,ZHANG Zhe,ZHANG Zhi-yong.Content change of triptolide in Tripterygium wilfordii compatible with four Chinese crude drugs[J].West China Journal of Pharmaceutical Sciences,2007,22(4):431-432. | |
| Authors: | WANG Yu ZHANG Zhe ZHANG Zhi-yong |
| Institution: | 1. West China Hospital, Siehuan University, Chengdu 610041, China ;2. West China School of Pharmacy, Siehuan University, Chengdu 610041 , China |
| Abstract: | OBJECTIVE To determine the content variation of triptolide when Tripterygium wilfordii respective compatible with Red Peony Root,Radish Seed,Finger Citron and Bamboo Shavings,and to study the rationality of the traditional Chinese drug compatibility.METHODS Decocted respectively the Tripterygium wilfordii and the four Chinese crude drugs with water,and evaluated the triptolide by HPLC.RESULTS The content of triptolide in the decoction of Tripterygium wilfordii compatible with Finger Citron was higher than Tripterygium wilfordii by 25% with statistical treatment,while the content in others had no significant change.CONCLUSION Finger Citron may obviously increase the content of triptolide.Red Peony Root,Radish Seed and Bamboo Shavings had quiet influence on it. |
| Keywords: | Tripterygium wilfordii Compatibility Triptolide |
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