| EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS |
| |
| 作者姓名： | 李文忠 叶干运 杨忠民 陶明波 骆钧 王传基 季峰 |
| |
| 作者单位： | Institute of Dermatology CAMS，Nanjing，Institute of Dermatology，CAMS，Nanjing，Institute of Dermatology，CAMS，Nanjing，Station for Skin Diseases Control，Yangzhou，Station for Skin Diseases Control，Yangzhou，Station for Skin Diseases Control，Yangzhou，Station for Skin Diseases Control，Dongtai County，Jiangsu Province. |
| |
| 摘 要： | The feasibility and effects of a 3-year treatment using rifampicin(RFP),clofazimine(B663)and dapsone(DDS)in multibacillary leprosy patients in Yangzhou Prefecture and DongtaiCounty(1983-1986)are reported.Among 591 active multibaeillary leprosy patients in thetwo areas,569 (96.30%)were treated with this regimen.of 303 cases available for analysis,196(64.7%)cases showed negative skin smears and clinical inactivity.The rest showeddifferent degrees of improvement.The average reduction of BI was 0.78.The intensityand frequency of ENL and neuritis decreased markedly with treatment.The main side-effects were pigmentation and ichthyosiform changes of the skin,but these did not influencetreatment.
|
EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS |
| |
| Li Wenzhong,Ye Ganyun,Yang Zhongmin,Tao Mingbo,Luo Jun,Wang Chuanji,Ji Feng Institute of Dermatology,CAMS,Nanjing Station for Skin Diseases Control,Yangzhou,Station for Skin Diseases Control,Dongtai County,Jiangsu Province..EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS[J].Chinese Medical Sciences Journal,1990(1). |
| |
| Authors: | Li Wenzhong Ye Ganyun Yang Zhongmin Tao Mingbo Luo Jun Wang Chuanji Ji Feng Institute of Dermatology CAMS Nanjing Station for Skin Diseases Control Yangzhou Station for Skin Diseases Control Dongtai County Jiangsu Province |
| |
| Abstract: | The feasibility and effects of a 3-year treatment using rifampicin(RFP),clofazimine(B663) and dapsone(DDS)in multibacillary leprosy patients in Yangzhou Prefecture and Dongtai County(1983-1986)are reported.Among 591 active multibaeillary leprosy patients in the two areas,569 (96.30%)were treated with this regimen.of 303 cases available for analysis, 196(64.7%)cases showed negative skin smears and clinical inactivity.The rest showed different degrees of improvement.The average reduction of BI was 0.78.The intensity and frequency of ENL and neuritis decreased markedly with treatment.The main side- effects were pigmentation and ichthyosiform changes of the skin,but these did not influence treatment. |
| |
| Keywords: | leprosy multidrug therapy |
| 本文献已被 CNKI 等数据库收录！ |
