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特异性转移因子对肺癌的免疫治疗
引用本文:沈丽英 苏成芝. 特异性转移因子对肺癌的免疫治疗[J]. 解放军医学杂志, 1990, 15(3): 198-200
作者姓名:沈丽英 苏成芝
作者单位:第四军医大学西京医院呼吸内科,第四军医大学西京医院呼吸内科,第四军医大学西京医院呼吸内科,第四军医大学西京医院呼吸内科,第四军医大学西京医院呼吸内科,第四军医大学西京医院呼吸内科,第四军医大学生化教研室,第四军医大学生化教研室,第四军医大学生化教研室 进修医师,进修医师
摘    要:

关 键 词:肺癌 转移因子 免疫疗法

SPECIFIC TRANSFER FACTOR IN THE IMMUNOTHERAPY OF LUNG CARCINOMA
Shen Liying.Zhang Xia.Cui Xueqing,Cheng Yiping,Wu Chengqian,Sun Shuping,Su Chengzhi,Wan Zhifang.Xu Weimin.Fourth Military Medical College,Xi-an. SPECIFIC TRANSFER FACTOR IN THE IMMUNOTHERAPY OF LUNG CARCINOMA[J]. Medical Journal of Chinese People's Liberation Army, 1990, 15(3): 198-200
Authors:Shen Liying.Zhang Xia.Cui Xueqing  Cheng Yiping  Wu Chengqian  Sun Shuping  Su Chengzhi  Wan Zhifang.Xu Weimin.Fourth Military Medical College  Xi-an
Abstract:A series of 50 patients with lung carcinoma were studied to evaluate the clinical and immune effects of specific transfer factor (SPTF).The SPTF group (n=35) received both chemotherapy and SPTP treatment,which was administered by intramuscular injection 2ml (2 unit) twice a week for 4 weeks.The control group (n=15) received only chemotherapy.During the treatment the sideeffects of chemotherapy in the SPTF group were significantly lower than that of the control group.Peripheral blood T-lymphocyte subsets were determined by OKT McAb.There were significant differences in OKT4,OKT8,OKT4/OKT8 ratio before and after the administration of SPTF (P<0.001).There were no differences in the control group.The results of the study suggest that the specific immunothe-rapy by means of SPTF can increase the immune competence of patients with lung cancer.SPTF has been proved to have antigen-specific activities,without side effects.
Keywords:Specific transfer factor of lung carcinoma Lung carcinoma Immunotherapy
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