| 运动锻炼对局灶性脑缺血大鼠脑皮质RGMa表达的影响 |
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| 引用本文： | 郭振委,秦新月,孔渝菡.运动锻炼对局灶性脑缺血大鼠脑皮质RGMa表达的影响[J].重庆医科大学学报,2011,36(5):578-582. |
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| 作者姓名： | 郭振委 秦新月 孔渝菡 |
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| 作者单位： | 重庆医科大学附属第一医院神经内科,重庆市高校神经病学重点实验室,重庆400016 |
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| 基金项目： | 国家自然科学基金资助项目，重庆医科大学附属第一医院基金资助项目 |
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| 摘 要： | 目的:探讨运动锻炼对卒中后大鼠缺血侧脑皮质排斥性导向分子A(Repulsive guidance molecule A,RGMa)表达的影响.方法:选用SD大鼠120只,随机分为5组,正常组,假手术组,MCAo模型7、14、28 d组,以上各组再分为:非运动、低运动量、中动量、高动量锻炼组,每组6只.应用线栓法制备局灶...
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| 关 键 词： | 运动锻炼 脑缺血 排斥性导向分子A 实时定量PCR |
Effects of treadmill exercise on the expression of RGMa in infarcted brain cortex of rats after middle cerebral artery occlusion/reperfusion |
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| GUO Zhen-wei,QIN Xin-yue,KONG Yu-han.Effects of treadmill exercise on the expression of RGMa in infarcted brain cortex of rats after middle cerebral artery occlusion/reperfusion[J].Journal of Chongqing Medical University,2011,36(5):578-582. |
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| Authors: | GUO Zhen-wei QIN Xin-yue KONG Yu-han |
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| Institution: | GUO Zhen-wei,QIN Xin-yue,KONG Yu-han(Department of Neurology,the First Affiliated Hospital,Chongqing Medical University) |
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| Abstract: | Objective:To observe the expression of RGMa in infarcted brain cortex of rats with middle cerebral artery occlusion(MCAo)after experiencing treadmill exercise.Methods:120 Sprague-Dawley rats were randomly divided into 5 groups:control group,sham-operation group,and 7,14,28 d after ischemia group.Then each group above were randomly divided into four groups:sedentary group,low-intensity,moderate-intensity,high-intensity treadmill exercise group with MCAo.The MCAo/reperfusion model was induced by ligation with... |
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| Keywords: | treadmill exercise cerebral ischemia RGMa RT-qPCR |
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