| 中枢5-羟色胺和鸦片样物质在针刺镇痛中的作用 |
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| 引用本文： | 韩济生,汤健,范少光,任民峰,周仲福,张万琴,梁熙南. 中枢5-羟色胺和鸦片样物质在针刺镇痛中的作用[J]. 针刺研究, 1980, 0(1) |
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| 作者姓名： | 韩济生 汤健 范少光 任民峰 周仲福 张万琴 梁熙南 |
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| 作者单位： | 北京医学院基础部针麻原理研究组生理组，北京医学院基础部针麻原理研究组生理组，北京医学院基础部针麻原理研究组生理组，北京医学院基础部针麻原理研究组生理组，北京医学院基础部针麻原理研究组生理组，遵义医学院，广西医学院 |
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| 摘 要： | <正> 针灸疗法是中国传统医学中治疗疼痛性疾病的经典方法之一。近年来临床上针刺麻醉的应用,大大促进了关于针刺镇痛问题的研究。在西方医学中,近年来关于吗啡镇痛和脑刺激镇痛的研究,以及内源性鸦片样物质的发现,使疼痛和镇痛的研究得到长足的
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CENTRAL 5-HYDROXYTRYPTAMINE,OPIATELIKE SUBSTANCES AND ACUPUNCTURE ANALGESIA |
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| Abstract: | The effect of acupuncture analgesia in rat was assessed by the tail-flick method and was triedto correlate with the changes in the cerebral content of serotonin(5-HT)and the endogenous opiate-like substances(OLS),Measures were taken to lower the cerebral content of 5-HT or to block theeffect of OLS to see their effect on acupuncture analgesia.The interrelationship between 5-HTcontent and OLS activity was also monitored in different physiological and pharmacologicalsituations.The results indicated that the effect of acupuncture analgesia was intimately related to thecerebral 5-HT content and OLS activity and the extent to which they were mobilized during thecourse of acupuncture.There was an intimate interrelationship between the cerebral 5-HT contentand the OLS activity and these two neurochemical substrates seemed to be functionally compensatoryto each other. |
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