灵芝多糖的急性毒性和抗肿瘤作用 |
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引用本文: | 崔永伟.灵芝多糖的急性毒性和抗肿瘤作用[J].中国当代医药,2012,19(2):46-47. |
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作者姓名: | 崔永伟 |
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作者单位: | 江苏省溧水县中医院药剂科,江苏溧水,211200 |
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摘 要: | 目的:探讨灵芝多糖的急性毒性和抗肿瘤作用。方法:观察灵芝多糖的LD50及对S180小鼠肉瘤细胞的抑制作用。结果:灵芝多糖的LD50远大于国家标准15g/kg,属无毒级别。同时当灵芝多糖的剂量为250mg/kg时,对S180小鼠肉瘤细胞的抑瘤率为43.44%。结论:灵芝多糖有很好的抗肿瘤作用,同时无急性毒性,值得推广应用。
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关 键 词: | 灵芝多糖 急性毒性 抗肿瘤作用 中药 |
The acute toxicity and antitumor of ganoderma lucidum polvsaccharides |
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Authors: | CUI Yongwei |
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Institution: | CUI Yongwei Pharmacy of Lishui County Hospital in Jiangsu Province, Lishui 211200, China |
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Abstract: | Objective: To investigate the acute toxicity and antitumor of ganoderma lucidum polysaccharides. Methods: Observed the inhibition of the LD50 of ganoderma lucidum polysaccharides to the mouse sarcoma S180 cells. Results: The results showed that the LD50 of the ganoderma lucidum polysaccharides were greater than the national standard of 15 g/kg, it had non-toxic. At the same time, when the dose of Ganoderma lucidum polysaccharides was 250 mg/kg, the inhibition was 43.44% of S180 mouse sarcoma cells. Conclusion: Ganoderma lucidum polysaccharides has a good anti-tumor effect, and no acute toxicity, should be widely applied. |
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Keywords: | Ganoderma lucidum polysaccharides Acute toxicity Anti-tumor effect Traditional Chinese medicine |
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