小剂量米非司酮治疗子宫腺肌病临床观察

目的：探讨小剂量米非司酮治疗子宫腺肌病的临床疗效。方法：选择本院2009年6月～2011年6月收治的50例子宫腺肌病患者,给予米非司酮10mg/d,连用6个月,观察用药前后患者的疼痛程度、月经周期、经期、子宫体积等指标变化情况。结果：50例患者痛经程度用药后与用药前比较明显减低,月经量明显减少,月经周期趋于正常,子宫体积明显减小,差异有统计学意义（P〈0.05）。结论：小剂量米非司酮治疗子宫腺肌病疗效显著,值得临床推广应用。

Clinical observation of low dose of mifepristone in the treatment of adenomvosis

Objective: To investigate the clinical effect of low dose of mifepristone in the treatment of adenomyosis. Methods: Chose 50 cases with adenomyosis in our hospital from June 2009 to June 2011, who were treated with 10 mg/d of mifepristone, used six months, observed the changes of pain degree, menstrual cycle, menstrual period, uterine volume before and after drug. Results: The pain degree of 50 patients decreased significantly compared with that before drug, menstrual amount was reduced, menstrual cycle tended to be normal, uterine volume was reduced significantly, there was significant statistical difference (P<0.05). Conclusion: The clinical effect of low dose of mifepristone in the treatment of adenomyosis is positive, it is worthy of clinical application.