| 肠促胰素在2型糖尿病治疗中的作用 |
| |
| 引用本文： | 纪立农.肠促胰素在2型糖尿病治疗中的作用[J].中华内分泌代谢杂志,2010,26(8). |
| |
| 作者姓名： | 纪立农 |
| |
| 作者单位： | 北京大学糖尿病中心、北京大学人民医院内分泌科,100044 |
| |
| 摘 要： | 肠促胰素是经食物刺激后由肠道细胞分泌入血、具有促进胰岛素分泌作用的一类激素;人体中,胰升糖素样肽1(GLP-1)和糖依赖性胰岛素释放肽(GIP)发挥肠促胰素效应.根据近期发表的研究,本文回顾了肠促胰素的生理作用,同时阐述了 GIP和GLP-1在2型糖尿病治疗中的特点.
|
| 关 键 词： | 肠促胰素 胰升糖素样肽1 糖依赖性胰岛素释放肽 糖尿病 2型 |
Effects of incretin in the treatment of type 2 diabetes |
| |
| JI Li-nong.Effects of incretin in the treatment of type 2 diabetes[J].Chinese Journal of Endocrinology and Metabolism,2010,26(8). |
| |
| Authors: | JI Li-nong |
| |
| Abstract: | Incretin hormones are defined as intestinal hormones released in response to nutrient ingestion,and potentiate the glucose-induced insulin response. In humans, the incretin effect is mainly caused by two peptidehormones, glucagon-like peptide-1 ( GLP-1 ) and glucose-dependent insulin releasing polypeptide (GIP). According to the recently finished studies, the review focuses on the physiological actions of incretin, explains the different insulinotropic actions of GLP-1 and GIP in type 2 diabetic patients, and evaluates the clinical features of recently approved therapeutic agents based on incretin action. |
| |
| Keywords: | Incretin Glucagon-like peptide-1 Glucose-dependent insulinotropic peptide Diabetes mellitus type 2 |
| 本文献已被 万方数据 等数据库收录！ |
