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氯沙坦对老年高血压病患者左室功能改善的临床观察
引用本文:付军,黄晶,吴绥生,王强.氯沙坦对老年高血压病患者左室功能改善的临床观察[J].中国老年学杂志,2001,21(2):101-102.
作者姓名:付军  黄晶  吴绥生  王强
作者单位:1. 吉林大学第一医院,吉林 长春 130021
2. 吉林大学中日联谊医院
摘    要:目的 观察氯沙坦对老年高血压左室肥厚病人左室舒张的影响。方法 对43例老年高血压左室肥厚患者口服氯沙坦(50-100mg/d)治疗12-17个月,应用平稳法放射性核素心室造影,观察其治疗前后左室舒张功能改善情况。结果 治疗后较治疗前左室舒张功能得到明显改善(P<0.05)。结论 氯沙坦在有效降压的同时,明显改善左室舒张功能。

关 键 词:氯沙坦  高血压  左室舒张功能  药物疗法  老年人  治疗
文章编号:1005-9202(2001)02-0101-02
修稿时间:2000年8月4日

Clinical study of improvement of losartan on left ventricular function in aged patients with hypertension
Abstract:Objective To observe the effects of losarta n on left ventriculardiastolic function in aged patients with hypertension and left ventricular hypertrophy.Methods Forty-three elderly patients with hypertension a nd left ventricular hypertrophy were treated with losartan 50~100 mg by oral ev ery day for 12~17 months.Clinical study of improvement on left ventricular dias tolic function was studied with equilibrium radionuclide ventriculography.Results After the therapy with losartan left ventricular di astolic function was improved significantly(P<0.05) compared with before.Conclusions The results prove that treatment with losarta n can decrease blood pressure and improve left ventricular distolic function in aged patients with hypertension.
Keywords:? Losartan  Elderly hypertension  Left ventricular diastolic function
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