血管内皮生长因子-C与肺癌 |
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引用本文: | 陈玉,齐协飞. 血管内皮生长因子-C与肺癌[J]. 国际肿瘤学杂志, 2002, 36(1): 434-436. DOI: 10.3760/cma.j.issn.1673-422X.2009.06.012 |
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作者姓名: | 陈玉 齐协飞 |
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作者单位: | 南昌大学第二附属医院呼吸内科,330006; |
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摘 要: | 血管内皮生长因子-C(VEGF-C)可以与血管及淋巴管内皮上的特异性受体结合,加速肺癌的形成及转移.同时对恶性胸腔积液的生成、免疫调节因子的表达也有着特殊作用.目前国内外研究均显示VEGF-C的抑制有望成为治疗肺癌的新靶点.
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关 键 词: | 血管内皮生长因子C 肺肿瘤 胸腔积液 |
VEGF-C and lung cancer |
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Abstract: | Vascular endothelial growth factor-C (VEGF-C) binds to special receptors on the vessel and lymphatic endothelium to accelerate the formation and metastasis of lung cancer. It shows specific action on malignant pleural effusion formation and immuno-regulation factor expression. It is reported that inhibition of VEGF-C would be a target point in lung cancer therapy. |
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Keywords: | Vascular endothelial growth factor CLung neoplasmsPleural effusion |
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