颅脑手术后颅内感染危险因素分析研究

目的探讨颅脑手术后颅内感染的危险因素。方法以病例对照研究的方法研究患者颅内感染的危险因素，采用检验和logistic回归分析方法研究各因素与颅内感染的关系。结果急诊手术、术后放置引流管、手术时间长、后颅凹部位手术、脑脊液漏、切口积液与术后颅内感染呈显著相关（P＜0.05）；患者的性别、年龄、术前是否应用抗生素与颅内感染无显著相关。结论急诊手术、术后放置引流管、手术持续时间、手术部位、脑脊液漏、切口积液是术后颅内感染的危险因素。

Risk factors of intra-cranial infection after craniotomy

Objective To investigate risk factors of intra-cranial infection after craniotomy. Methods A case-control study was carried out and a chi-square test and logistic regression were used to analyze the relationship between the factors and intracranial infection. Results There were significant links between emergent operation, post-operative drainage tubes, duration of operation time, posterior fossa surgery, cerebrospinal fluid leakage, wound fluid and intra-cranial infection after craniotomy ( P < 0.05) . There were no significant links between gender, age, use of antibiotics before surgery and intra-cranial infection after craniotomy. Conclusion Emergent operation, post-operative drainage tubes, duration of operation time, posterior fossa surgery, cerebrospinal fluid leakage and wound fluid are risk factors of intracranial infection after craniotomy.