进展性脑梗死相关危险因素分析

目的探寻引起脑梗死进展的相关危险因素。方法对我院2008年5月-2011年5月住院的急性脑梗死患者246例,根据入院后病情演变分为进展性脑梗死组(PCI)和非进展性脑梗死组(NPCI)。观察项目包括年龄、高血压史、糖尿病史、冠心病史、脑卒中病史、高脂血症史、吸烟史及饮酒史,入院时神经功能评分、入院时高血压、入院后血压降低、发热、血脂、血糖、红细胞压积、颈动脉狭窄及颅内动脉狭窄进行分析。结果 PCI组的糖尿病史、早期不适当降压治疗、颅内动脉狭窄、颈动脉狭窄、入院后24小时内最高体温、白细胞计数、空腹血糖及侧脑室旁梗死差异有显著统计学意义。结论糖尿病病史、早期不适当降压治疗、发热、白细胞计数增高、空腹血糖增高、劲内动脉和颅内动脉狭窄及侧脑室旁梗死是引起脑梗死进展的主要危险因素。

Analysis of related risk factors of progressive ischemic cerebral infarction

Objective To investigate the related risk factors that caused progressive ischemic cerebral stroke. Methods 246 cases which were admissioned our hospital from May 2008 to May 2011 were studied retrospectively, according to evolving clinical course, which were labelled into progressive cerebral infarction （PCI） group and nonprogressive cerebral infarction （ NPCI ） group, studied items included age, history of hypertension, diabtes millitus, coronary heart disease, stroke, hyperlipoeholemia, smoking and alcohol drinking, scores of neurological function, blood pressure of admission, the decreasing of blood pressure after admission, fever , serum lipoprotein level , serum glucose, heamocfits, stenosis of carotid and intraeranial arteries, then analysized them respectively. Results History of Diabtes Millitus, early decreasing blood pressure , temputure of admission 24 hours, leukocytes counting, serum glaucose, infarction lesion adjacent to lateral ventrieals, stenosis of intracranial and internal carotid arteries were more signifiantly in statistics in PC1 group than that of NPCI group （ P 〈 0.05 ）. Conclusion PCI is related to those risk factors of history of Diabtes Millitus, early decreasing blood pressure, fever , leukocytes increasing, elevating serum glucose , infarction lesion adjacent to lateral ventrieals, stenosis of intracranial and internal carotid arteries.