妊娠合并甲状腺功能异常187例临床分析

目的探讨妊娠合并甲状腺功能亢进或减退对妊娠结局的影响。方法回顾性分析，1999年至2008年187例妊娠合并甲状腺功能异常患者的妊娠结局及其影响因素。结果妊娠合并甲亢发病率程逐年下降趋势，基本稳定在1‰左右，妊娠合并甲减发病率程逐年上升趋势；妊娠合并甲亢患者，治疗与未治疗产科并发症发生率分别为38．2％与42．9％，妊娠合并甲减患者，治疗与未治疗产科并发症发生率分别为48．9％与71．4％，差异均具有统计学意义。结论对妊娠合并甲状腺功能异常者进行早期筛查、诊断并及时给予治疗，可有效降低不良妊娠结局发生。

Pregnancy combined with thyroid disorder : analysis of 187 cases

Objective： To evaluate the effect of thyroid disorder on pregnancy. Methods ： A retrospective analysis of the pregnancy outcomes in 187 pregnant women combined with thyroid disorder from 1999 to 2008. Result： The incidence of pregnancy combined with hyperthyroidism decreases year by year, and basically stabled at about 1‰, while the incidence of pregnancy combined with hypothyroidism displays a upward trend year by year. The incidence-of obstetric complications during pregnancy combined with hyperthyroidism between treatment and non - treatment are 38.2% and 42. 9% respectively while the incidence of obstetric complications during pregnancy combined with hypothyroidism between treatment and non -treatment are 48.9% and 71.4% respectively, and both of the differences have statistically significance. Conclusions： Pregnancy combined with thyroid disorder in early screening, diagnosis and timely treatment, could effectively reduce the occurrence of adverse pregnancy outcomes.