Serum gastrin concentrations in colorectal cancer patients. |
| |
Authors: | R. M. Charnley W. M. Thomas J. Stanley D. L. Morris |
| |
Affiliation: | Department of Surgery, University Hospital, Nottingham. |
| |
Abstract: | Fasting serum gastrin concentrations were shown to be elevated in colorectal cancer patients compared with controls (P = 0.0037), which was mainly accounted for by a subgroup of patients who had significantly elevated levels. In cancer patients there was no difference in gastrin concentrations in blood taken from a tumour-draining mesenteric vein and from a peripheral vein at the time of colonic resection. Serum gastrin concentrations were significantly lower after apparently curative resection for colorectal cancer (P = 0.028), suggesting that the elevated serum gastrin seen in these patients may be due, at least in part, to secretion of gastrin by the tumour. |
| |
Keywords: | |
|
|