幕上高血压性脑出血微创颅内血肿抽吸引流术1年预后相关因素分析

目的 探讨幕上高血压性脑出血（intracerebral h emorrhage，ICH）微创颅内血肿抽吸引流术1年预后及其相关因素。 

Analysis of Related Factors of 1-year Outcome of Minimally Invasive Surgery in Supratentorial Spontaneous Intracerebral Hemorrhage

Objective To study 1-year clinical outcomes after minimally invasive catheter evacuation followed
by urokinase for clot removal in patients with acute supratentorial spontaneous intracerebral
hemorrhage (ICH) and determine the factors associated with the 1-year outcome.
Methods Supratentorial spontaneous ICH patients who had undergone minimally invasive catheter
evacuation followed by urokinase for clot removal during January 2014 and September 2016
were collected . Patients' demographic and clinical information, surgery information and one-year
modified Rankin scale (mRS) were recorded. The main clinical outcome was poor outcome, defined
as mRS score >3 at 1 year. The multi-factor logistic regression analysis was used to determine
factors associated with 1-year clinical outcome after ICH.
Results A total of 117 patients with supratentorial spontaneous ICH and having undergone minimally
invasive surgery were enrolled in the study. The mean age was (56.5±12.5) years and the mean
baseline hematoma volume was (59.0±28.5) ml. 59 (50.4%) ICH patients had 1-year poor outcome
after surgery. Multi-factor Logistic regression analysis revealed that baseline hematoma volume 20-50
ml odds ratio (OR) 0.161, 95% confidence interval (CI) 0.034-0.748, P =0.020] and age≤60 years (OR0.169, 95%CI 0.055-0.515, P =0.002) were independent protective factors of 1-year poor outcome.
Conclusion Baseline hematoma volume and age were independent predictors of 1-year outcome
in acute ICH patients who had undergone minimally invasive surgery, which could allow better
selection of ICH patients appropriate for minimally invasive surgery.