| 联合检测血清CA153和TSGF对胶质瘤的诊断价值 |
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| 引用本文： | 许州,袁先厚,江普查,陈锋,刘细国.联合检测血清CA153和TSGF对胶质瘤的诊断价值[J].肿瘤防治研究,2009,36(12):1054-1056. |
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| 作者姓名： | 许州 袁先厚 江普查 陈锋 刘细国 |
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| 作者单位： | 430071 武汉大学中南医院神经外科 |
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| 摘 要： | 目的探讨血清CA153和TSGF联合检测在胶质瘤诊断中的价值。方法采用免疫放射量度分析法和分光光度比色法测定58例胶质瘤患者血清中CA153和TSGF的表达水平。结果胶质瘤患者血清中CA153和TSGF的表达水平明显高于脑非胶质瘤良性肿瘤和健康对照组（P<0.05）,低级别胶质瘤与高级别胶质瘤之间表达水平差异亦有统计学意义（P<0.05）,两者联合检测能提高对脑胶质瘤的诊断率。结论联合检测血清CA153和TSGF对脑胶质瘤的早期诊断和判断恶性程度及预后有重要参考价值。
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| 关 键 词： | 胶质瘤 CA153 恶性肿瘤特异性生长因子 |
| 收稿时间： | 2008-8-5 |
| 修稿时间： | 2008-11-21 |
Evaluation of Combined Determination of Serum CA153 and TSGF in Diagnosis of Human Gliomas |
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| XU Zhou,YUAN Xian-hou,JIANG Pu-cha,CHEN Feng,LIU Xi-guo.Evaluation of Combined Determination of Serum CA153 and TSGF in Diagnosis of Human Gliomas[J].Cancer Research on Prevention and Treatment,2009,36(12):1054-1056. |
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| Authors: | XU Zhou YUAN Xian-hou JIANG Pu-cha CHEN Feng LIU Xi-guo |
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| Institution: | Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Wuhan 430071, China |
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| Abstract: | Objective To investigate the evaluation of combined determination of serum CA153 and TSGF in diagnosis of gliomas. Methods Immune radiation measure analysis and Spectro-photometric method were used to detect the serum level of CA153 and TSGF in 58 patients having gliomas. Results The serum level of CA153 and TSGF of the gliomas group was significant higher than that of the The benign tumor group and healthy group(P<0. 05). The serum level of CA153 and TSGF in gliomas with different degrees of malignant was significantly different(P<0. 05). Diagnostic efficiency of combined determination of serum CA153 and TSGF were higher than those of the single index in diagnosis of gliomas. Conclusion Combined determination of CA153 and TSGF plays an important role in early diagnosis pathologic stage and prognosis of gliomas. |
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| Keywords: | CA153 Gliomas CA153 TSGF |
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