Hydrogen sulfide: physiological properties and therapeutic potential in ischaemia |
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| Authors: | Eelke M Bos Harry van Goor Jaap A Joles Matthew Whiteman Henri G D Leuvenink |
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| Affiliation: | 1Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;2Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;3Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands;4Peninsula Medical School, University of Exeter, Exeter, Devon, UK |
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| Abstract: | Hydrogen sulfide (H2S) has become a molecule of high interest in recent years, and it is now recognized as the third gasotransmitter in addition to nitric oxide and carbon monoxide. In this review, we discuss the recent literature on the physiology of endogenous and exogenous H2S, focusing upon the protective effects of hydrogen sulfide in models of hypoxia and ischaemia.Linked ArticlesThis article is part of a themed section on Pharmacology of the Gasotransmitters. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2015.172.issue-6 |
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