Resolution of dilated cardiomyopathy in an adolescent with change of a failing highly active antiretroviral drug therapy |
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Authors: | Twalib Olega Aliku Sulaiman Lubega Peter Lwabi |
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Affiliation: | 1 Department of Paediatrics and Child Health, Gulu University;2 Uganda Heart Institute, Mulago Hospital Complex |
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Abstract: | BackgroundCardiovascular dysfunction is a recognized complication of HIV infection in children. Cardiac complications of HIV usually occur late in the course of the disease; they may be associated with drug therapy, and hence become more common as therapy and survival improve. Left ventricular (LV) dysfunction at baseline is a risk factor for death independent of the CD4 cell count, HIV viral load, and neurological disease.ConclusionImmunological recovery following a switch of a failing or potentially cardiotoxic HAART in addition to improved HAART adherence may result in resolution of left ventricular dysfunction. Early and regular cardiology evaluation may improve outcomes in these patients. |
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Keywords: | Dilated Cardiomyopathy HAART |
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