| 酒石酸锑钾和葡萄糖酸锑钠合并应用的毒性研究 |
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| 引用本文： | 张效文,沈道修.酒石酸锑钾和葡萄糖酸锑钠合并应用的毒性研究[J].药学学报,1964,11(8):568-570. |
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| 作者姓名： | 张效文 沈道修 |
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| 作者单位： | 上海第二医学院药理教研组，上海第二医学院药理教研组 上海中医学院中药研究室药理组 |
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| 摘 要： | 本文用Loewe图解分析法分析了五价葡萄糖酸锑钠与三价酒石酸锑钾合并应用时对小白鼠的毒性。结果发现用五价葡萄糖酸锑钠LD50的1/4,1/2及3/4的剂量分别与三价酒石酸锑钾合并应用时,二种锑剂的毒性间有明显的对抗作用。
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| 收稿时间： | 1963-01-02 |
STUDIES ON THE COMBINED TOXICITY OF TARTAR EMETIC AND SODIUM ANTIMONY GLUCONATE |
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| CHANG HSIAO-WEN SHEN DAO-HSIU.STUDIES ON THE COMBINED TOXICITY OF TARTAR EMETIC AND SODIUM ANTIMONY GLUCONATE[J].Acta Pharmaceutica Sinica,1964,11(8):568-570. |
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| Authors: | CHANG HSIAO-WEN SHEN DAO-HSIU |
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| Abstract: | The combined toxicity of sodium antimony gluconate (SAGsbv) and tartar emetic (PATsbⅢ) was analysed in mice according to Loewe's method. It was found that when sodium antimony gluconate in the doses of 1/4, 1/2, and 3/4 respectively of its LD50 was used in combination with tartar emetic, a marked antagonistic effect in their toxicities occured. |
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