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从苦参中提取以氧化苦参碱为主的苦参总碱的工艺研究
引用本文:何世宇,廉蕊,张国刚. 从苦参中提取以氧化苦参碱为主的苦参总碱的工艺研究[J]. 实用中医内科杂志, 2010, 24(7): 22-23. DOI: 10.3969/j.issn.1671-7813.2010.07.12
作者姓名:何世宇  廉蕊  张国刚
作者单位:1. 沈阳合信生物工程有限公司,辽宁沈阳,110015
2. 沈阳药科大学天然药化实验室,辽宁沈阳,110016
摘    要:[目的]通过对苦参提取工艺的研究,寻找适合于提取苦参总碱的方法。[方法]对几种从苦参中提取生物碱的主要方法进行比较,选择树脂法为本次工艺研究的实验方法。[结果]苦参总碱的收率在4~7之间,平均值为5.87。氧化苦参碱的含量也在75%~80%之间,平均值为76.38%。[结论]用树脂法提取以氧化苦参碱为主的苦参总碱,提高了其产品的收率和含量。为企业大批量生产提供了有效数据。

关 键 词:苦参  氧化苦参碱  提取

Study On Percolation Processes of Matrine Mainly Containing Oxymatrine in Sophora Flavescens Ait
HE Shi-yu,LIAN Rui,ZHANG Guo-gang. Study On Percolation Processes of Matrine Mainly Containing Oxymatrine in Sophora Flavescens Ait[J]. , 2010, 24(7): 22-23. DOI: 10.3969/j.issn.1671-7813.2010.07.12
Authors:HE Shi-yu  LIAN Rui  ZHANG Guo-gang
Affiliation:HE Shi-yu ,LIAN Rui ,ZHANG Guo- gang (1. Shenyang Hexin Biological Engineering Co. , Ltd. ,Shenyang 110015 ,Liaoning,China; 2. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, China)
Abstract:[ Objective] By studying on extraction of sophora flaveseens ait to look for business volume ex- traction method of matrine in sophora flavescens ait. [ Methods ] Compared several main methods of the alkaloids extracted from Sophora, we chose resin -based sub -process as the experimental method. [ Results ] The yield of matrine between 4 to 7, with an average 5.87. Oxymatrine content are 75% to 80% , average 76.38%. [ Conclusion] Resin extraction method of matrine which mainly contains oxymatrine improved its product yield and concentration. And the method also provided an effective data to the enterprise for the mass production.
Keywords:sophora flavescens air  oxymatrine  extraction
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