老年高血压治疗进展

老年人高血压有其特有的病理生理学特征,如血压波动大,易发生体位性低血压、对神经反射的敏感性降低、体液成分及血流动力学改变、合并多脏器功能损害等,在老年人群中收缩期高血压占很大的比例,降压治疗效果差,因此老年高血压的治疗应考虑其特点,本文综述了抗高血压药物在老年人群中的治疗进展,提出对于老年人高血压降压治疗应该多方面综合考虑,不仅要考虑血压的降低,而且要考虑老年人同时合并的疾病及各器官功能状态,降压药物从小剂量开始,联合用药才能达到理想的降压效果。

Advance of antihypertensive therapy in elderly patients with hypertension

There are special pathophysiologic characters in elderly patients with hypertension. Such as the undulation of blood pressure is more obviously and easy to result in orthostatic hypotension, the sensitivity to the nerve reflex reduces, the composition of body fluid and hemodynamics changes, and always complains with other organs incompetence. Isolate systolic hypertension is more general in older. The effect of antihypertension in these patients is poor. In lecture we review the advance of antihypertension in old patients, we suggest that the treatment of elder patients with hypertension should be colligated, not only reduce the blood pressure, but also considering the compliance and the fumction of other organs. The medication should begin at low dose, and combined treatment could obtain good results.