Diagnostic value of MR imaging in comparison to CT in the detection and differential diagnosis of renal masses: ROC analysis |
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Authors: | B P Kreft H Müller-Miny T Sommer A Steudel M Vahlensieck D Novak B G Müller H H Schild |
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Institution: | (1) Department of Radiology, University of Bonn, Sigmund-Freud-Strasse 25, D-53 127 Bonn, Germany, DE;(2) Department of Urology, University of Bonn, Sigmund-Freud-Strasse 25, D-53 127 Bonn, Germany, DE |
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Abstract: | The aim of this work was to compare MR imaging and CT in the detection of renal masses and in the differential diagnosis
between benign and malignant lesions. In 33 patients with 54 renal lesions CT and MR images were evaluated by four readers
with regard to tumor detection and characterization using a receiver-operating-characteristics (ROC) analysis. The MRI protocol
consisted of a T1-weighted spin-echo (SE) sequence (TR/TE: 300/10 ms) before and after contrast administration and a heavily
T2-weighted turbo-SE (TSE) sequence (TR/TE: 5500/150 ms). Az values for the area under the ROC curves for lesion detection were 0.92 ± 0.04 for CT and 0.91 ± 0.05 for MRI, respectively,
which was not statistically different. The MRI technique was slightly, but not significantly, better than CT in the overall
characterization (accuracy in differentiation between benign and malignant) of renal lesions with an Az value of 0.90 ± 0.05 compared with 0.88 ± 0.06 for CT. The MRI technique proved to be statistically superior to CT (p < 0.01) in the correct characterization of benign renal lesions. MRI equals CT in the overall detection and differential
diagnosis of renal masses. MRI is very helpful for further differential diagnosis of lesions which are equivocal on CT especially
in the differentiation between complicated cysts and cystic or hypovascular renal cell carcinoma.
Received 29 April 1996; Revision received 14 August 1996; Accepted 2 September 1996 |
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Keywords: | : Kidney Neoplasms MRI CT Kidney Renal lesions ROC curve |
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