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枇杷叶乙醇提取物降血糖的实验研究
引用本文:谢筱琳,钟颖.枇杷叶乙醇提取物降血糖的实验研究[J].中医药导报,2009,15(5).
作者姓名:谢筱琳  钟颖
作者单位:1. 湖南省荣军医院,湖南,长沙,410119
2. 湘西自治州人民医院,湖南,湘西,416000
摘    要:目的:观察枇杷叶乙醇提取物时正常小鼠及肾上腺素和葡萄糖引起的高血糖动物模型的作用.方法:采用注射肾上腺素和葡萄糖引起的高血糖动物模型及正常ICR小鼠,分别以枇杷叶提取物低、中、高剂量进行灌胃,给药结束后测定血糖水平.结果:提取物中、高剂量组在0.5h时有对抗肾上腺素的升血糖作用(P<0.05-0.01),高剂量组在1 h时能降低肾上腺性高血糖(P<0.05);提取物中、高荆量组对葡萄糖引起的血糖升高有抑制作用(P<0.05-0.01),提取物对正常小鼠的血糖值作用明显(P<0.05-0.01).结论:枇杷叶乙醇提取物对多种动物模型具有较好的降血糖作用.

关 键 词:枇杷叶  乙醇提取物  糖尿病小鼠

Experimental Studies on Hypoglycemic Effects of Alcohol Extracts From Eriobotrya japonica (Thumb.)Lindl
XIE Xiao-lin,ZHONG Yin.Experimental Studies on Hypoglycemic Effects of Alcohol Extracts From Eriobotrya japonica (Thumb.)Lindl[J].GUIDING JOURNAL OF TCM,2009,15(5).
Authors:XIE Xiao-lin  ZHONG Yin
Institution:XIE Xiao-lin1,ZHONG Yin2 1.Hunan Rongjun Hospital,Changsha,China,410119,2.Xiangxi Autonomy State People's Hospital,Xiangxi,Hunan,416000
Abstract:Objective:To observe hypoglycemic effects of alcohol extracts from Eriobotrya japonica(Thumb.)Lindl on various animal models.Methods:adopted animal model induced by epinephrine and glucose,and the normal mice.After taken the each dose drugs orally,the blood glucose levels of each model rat was determined.Results:The mid and high dose groups have better therapeutical action on diabetes mice induced by epinephrine in 0.5 h(P<0.05-0.01)and the high dose groups have better therapeutical action on diabetes mice ...
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