| 移植物抗宿主病动物模型的研究现状 |
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| 引用本文： | 吴涛,白海,王存邦. 移植物抗宿主病动物模型的研究现状[J]. 国际输血及血液学杂志, 2017, 40(1). DOI: 10.3760/cma.j.issn.1673-419X.2017.01.014 |
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| 作者姓名： | 吴涛 白海 王存邦 |
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| 作者单位： | 730050,兰州军区兰州总医院中国人民解放军血液病专科中心 |
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| 基金项目： | 甘肃省自然科学基金(145RJZA151)Natural Science Foundation of Gansu Province |
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| 摘 要： | 移植物抗宿主病(GVHD)是异基因造血干细胞移植(allo-HSCT)后影响患者生活质量和长期生存的重要因素,是导致allo-HSCT失败的主要原因之一.近年来,随着GVHD动物模型的长足发展,GVHD的病理生理学机制也有更深入的认识.笔者就近年来国内外GVHD动物模型研究进展进行综述.
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| 关 键 词： | 造血干细胞移植 移植物抗宿主病 模型,动物 |
Current situation of animal model on graft versus host disease |
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| Wu Tao,Bai Hai,Wang Cunbang. Current situation of animal model on graft versus host disease[J]. International Journal of Blood Tranfusion and Hematology, 2017, 40(1). DOI: 10.3760/cma.j.issn.1673-419X.2017.01.014 |
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| Authors: | Wu Tao Bai Hai Wang Cunbang |
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| Abstract: | Graft versus host disease(GVHD) is the important factor affecting the life quality and long survival of the allogeneic-hematopoietic stem cell transplantation (alIo-HSCT)patients.It is one of the major reasons to cause transplantation failure.In recent years,the hematologists have a better understanding of the mechanism of GVHD by the development of GVHD animal model.Here,the authors make a review of the progress of GVHD animal models. |
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| Keywords: | Hematopoietic stem cell transplantation Graft vs host disease Models,animal |
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