| Cogan综合征 |
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| 引用本文： | 刘广森,高磊. Cogan综合征[J]. 国际眼科纵览, 2017, 41(5). DOI: 10.3760/cma.j.issn.1673-5803.2017.05.008 |
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| 作者姓名： | 刘广森 高磊 |
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| 作者单位： | 1. 青岛大学附属烟台毓璜顶医院, 青岛大学,264000;2. 潍坊眼科医院, 青岛大学,261000 |
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| 摘 要： | Cogan综合征是一种罕见的以非梅毒性角膜基质炎及听觉-前庭功能障碍为特点的综合征,病因尚不明确,可能为自身免疫性疾病.多在青年人发病,主要表现为非梅毒性角膜基质炎和听觉前庭功能障碍.分为典型性和非典型性.需与肉芽肿性多血管炎、类风湿性关节炎、系统性红斑狼疮等鉴别.治疗以糖皮质激素、免疫抑制剂为主.
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| 关 键 词： | Cogan综合征 角膜基质炎 自身免疫性内耳疾病 血管炎 自身免疫 |
Cogan's syndrome |
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| LIU Guang-sen,GAO Lei. Cogan's syndrome[J]. International Review of Opthalmology, 2017, 41(5). DOI: 10.3760/cma.j.issn.1673-5803.2017.05.008 |
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| Authors: | LIU Guang-sen GAO Lei |
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| Abstract: | Cogan's syndrome (CS) is a rare disease,characterized by nonsyphilitic ocular keratitis and vestibuloauditory dysfunction.The cause of the disease is unclear.It may be an autoimmune disease.The inicidence of the disease is mostly young people.The main manifestation are nonsyphilitic ocular keratitis and vestibulo auditory dysfunction.The CS is divided into typical and atypical.It needs to differentiate with granulomatosis with polyangiitis,rheumatoid arthritis,systemic lupus erythematosus.The treatment is mainly with glucocorticoids and immunosuppressive agents. |
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| Keywords: | Cogan's syndrome interstitial keratitis autoimmune inner ear diseases vasculitis autoimmunity |
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