| 流感疫苗黏膜佐剂研究进展 |
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| 引用本文： | 李树香. 流感疫苗黏膜佐剂研究进展[J]. 国际生物制品学杂志, 2017, 40(4). DOI: 10.3760/cma.j.issn.1673-4211.2017.04.005 |
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| 作者姓名： | 李树香 |
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| 作者单位： | 国药中生生物技术研究院有限公司第三研究室,北京,101111 |
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| 摘 要： | 当前流感疫苗主要为肌内注射灭活疫苗和滴鼻减毒活疫苗.对于预防呼吸道传播的流感,抗原特异性黏膜免疫应答非常重要.现有资料显示,两种疫苗都存在不可避免的局限性,为解决这个问题,需要对黏膜佐剂流感疫苗进行深入的研究.此文对进入临床试验的流感疫苗黏膜佐剂进行综述.
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| 关 键 词： | 流感疫苗 佐剂,免疫 免疫,黏膜 |
Research progress in mucosal adjuvants for influenza vaccines |
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| Li Shuxiang. Research progress in mucosal adjuvants for influenza vaccines[J]. International Journal of Biologicals, 2017, 40(4). DOI: 10.3760/cma.j.issn.1673-4211.2017.04.005 |
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| Authors: | Li Shuxiang |
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| Abstract: | Current influenza vaccines mainly include intramuscular inactivated vaccines and intranasal attenuated live vaccines.Antigen-specific mucosal immune response is important for preventing influenza spread via respiratory transmission.Available data show that both vaccines have inevitable limitations.In order to solve this problem,in-depth studies on mucosal adjuvant influenza vaccines are needed.In this paper,the mucosal adjuvants used in influenza vaccines entered clinical trial are reviewed. |
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| Keywords: | Influenza vaccines Adjuvants,immunologic Immunity,mucosal |
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