Frequency of hepatic cysts in adult polycystic kidney disease

The frequency of hepatic cysts in patients with adult polycystic kidney disease (APKD) is usually considered to average about 33%, but with great, and hitherto largely unexplained, variations between different studies. Sixty-six consecutive patients with APKD were all subjected to CT scanning of the liver and of the kidneys. In confirmation of one previous study, a clearcut correlation was found between age (= duration of disease) and the frequency of hepatic cysts. It was furthermore found that cysts in the liver, as opposed to cysts in the kidneys, continue to grow and appear de novo even after institution of renal replacement therapy.