常规疗法伍用黄芪对病毒性心肌炎患者外周血T淋巴细胞亚群的影响

比较常规疗法伍用黄芪口服液与单用常规疗法对病毒性心肌炎患者外周血Ｔ淋巴细胞亚群影响。结果表明，病毒性心肌炎患者外周血Ｔ淋巴细胞亚群百分率及ＯＫＴ４／ＯＫＴ８比值显著低于健康对照者（Ｐ＜０．０５，０．０１）。常规疗法伍用黄芪可显著改善心肌炎患者ＯＫＴ３、ＯＫＴ４及ＯＫＴ４／ＯＫＴ８比值（Ｐ＜０．０５，０．０１）。并探讨了伍用黄芪改善病毒性，心肌炎患者细胞免疫状况可能的作用机理。

Effect of Astragalus membranaceus on T-Lymphocyte Subsets in Patients with Viral Myocarditis

The efficacy of Astragalus membranaceus(AM)oral liquor combined with routine therapy and routine therapy alone on T-lymphocyte subsets of peripheral blood in viral myocarditis patients have been studied.The results showed that the T-lymphocyte subsets profile and OKT 4/OKT 8ratio of peripheral blood were significantly lower in viral myocarditis patients than that in healthy control(P<0.05,0.01).Routine therapy combined with AM could significantly enhance OKT 3,OKT 4 and OKT 4/OKT 8 ratio in the above-mentioned patients (P<0.05,0.01).The possible pharmacodynamic mechanism of improved cell immunity in viral myocarditis patients by combining routine therapy with AM was discussed.